Nineteen of the Russian's twenty-one titles have been won on hard surfaces
A revitalized Medvedev claimed his maiden championship for over two years with success over Corentin Moutet in the competition championship match.
Medvedev, a former number one, has had a difficult period, achieving just one match at the Grand Slams and undergoing a setback at the American major.
Medvedev's unpredictability on the ATP Tour - and difficulties with his serving in particular - led to him exiting of the world's top 10 and finally parting ways with long-time coach his previous coach.
Now training with Thomas Johansson and Rohan Goetzke, he has consistently improved in the past month - culminating in a closely contested competitive victory over challenger Corentin Moutet.
This marks Medvedev's maiden championship following the Italian tournament and first on a hard court since spring of the previous year.
Victory also means he has won twenty-one championships at twenty-one distinct competitions.
"It's the first time I am participating in a competition with my both daughters together, so to win a championship is particularly special," commented ranked player the champion.
"This victory is in tribute of my second daughter Victoria, because the initial championship I achieved when my child Alisa was delivered was for her."
The athlete, the past champion, had failed in his previous six championship matches, comprising in the German tournament in the past months.
Medvedev's defensive strategy and recurring outbursts on the tennis court had led some to wonder if his ability to compete at the elite level was over.
But the 29-year-old has implemented adjustments in recent weeks, making an effort to come to the net and compete assertively, reinforced by an enhanced service.
Medvedev fought back from a deficit in the first set against the tricky opponent, securing 4 of the concluding five points to gain the advantage.
The competitors traded service breaks in the middle set before Moutet, attempting for his maiden tour victory, took control to create a decider.
The opponent saved 4 early break points in a tight final set before the Russian secured a break to 15 to secure the win.
Suitably, he earned victory with a shot at the net area, with the Frenchman incapable to handle a shot after a lengthy match.